I'm a Cleveland type collector. I have 2 goals. First is to get one of each type of card before 1990( there just got to be too many companies after that). Second is to get a card or photo of every player. I currently have around 1100 different players done. The want list is down below 500 for 1901-2011.
Many of my cards are graded. Some of the hi-lites are my Colavito Home Run Derby PSA 6, a Colavito Swift Meats PSA 10, a Jim Bagby E121 graded 84 by SGC. I also collect pins and have a nice Nig Cuppy Cameo Pepsin pin. It's a lot cheaper to get this pin than to try to find a Just So Tobacco card of him.
I also have a large number of Brace and Burke photos. These really come in handy for players in the 30's and 40's when there weren't many card sets. I seem to always have a wantlist with a #1 item I'm looking for. I'd say the item highest on my list right now is a 1928 Star Candy Garland Buckeye. I also would like to get a 1933 Butter cream, but so far I haven't been willing to pay the price that they go for.